DUTCH Adrenal Profile
Price range: $381.00 through $561.00
Comprehensive dried urine test measuring cortisol and cortisone patterns throughout the day, plus cortisol metabolites. Ideal for assessing adrenal function, stress response, and HPA axis dysregulation.
What is the DUTCH Adrenal Profile?
The DUTCH Adrenal Profile (Dried Urine Test for Comprehensive Hormones) by Precision Analytical is a specialised functional test that maps your adrenal function and stress hormone patterns. Unlike a single-point blood cortisol test, it captures your cortisol and cortisone levels across the entire day — revealing how your body produces, metabolises and clears stress hormones over a full diurnal cycle.
It is considered the clinical gold standard for assessing HPA (hypothalamic-pituitary-adrenal) axis function, and one of the most commonly ordered tests at Elemental Health for patients presenting with fatigue, sleep disturbance, anxiety and stress-related symptoms.
Is this test for you?
The DUTCH Adrenal Profile is for people who suspect their stress response is driving their symptoms:
- Persistent fatigue — especially “wired but tired” or morning exhaustion
- Difficulty falling asleep, waking at 2–4 AM, or unrefreshing sleep
- Anxiety, irritability, or feeling overwhelmed by minor stressors
- Afternoon energy crashes with sugar or caffeine cravings
- Chronic stress — work, relationship, or health-related
- Brain fog and poor concentration
- Recurrent illness or slow recovery from infection
- History of burnout, shift work, or prolonged high-demand periods
What it measures
Eight markers across four categories, mapping your cortisol curve, your body's ability to convert and clear stress hormones, and your adrenal reserve.
Diurnal Free Cortisol
Waking, morning, afternoon and evening — mapped against reference ranges to spot flat-line patterns, inverted rhythms or elevated evening cortisol.
Diurnal Free Cortisone
Cortisone is the inactive form of cortisol. Measuring both reveals how efficiently the 11β-HSD enzyme system converts between active and inactive forms.
Cortisol Metabolites
a-THF, b-THF, b-THE and a-THE — the only way to see total cortisol production, which can be high or low even when free cortisol looks normal.
DHEA-S
The primary adrenal androgen. Low DHEA-S relative to cortisol points to chronic stress and adrenal depletion.
Sample collection
Turnaround time
From the date the laboratory receives your sample.
Samples are processed in the United States by Precision Analytical's CLIA-certified laboratory — the same lab used by functional medicine practitioners worldwide.
How it works
Kit dispatched
Your DUTCH collection kit is posted directly to your door with full instructions.
Collect at home
Follow the simple guide to collect dried urine samples across the day.
Post back
Send your completed kit to the lab using the prepaid return envelope.
Results released
Your report is emailed to you the moment the lab releases it. What happens next depends on your tier —
- Test only: the report is yours to use as you see fit — no consultation included. You can book a separate consultation with Rohan later if you change your mind.
- Test + 60-min Telehealth Consult: once your results land, Rohan will email you a booking link to schedule your Zoom.
- Existing patients of the clinic: results are typically discussed at your next regular appointment as usual.
Why this test, why now?
Chronic stress is the most common driver of symptoms patients arrive with in clinic — fatigue, sleep disturbance, anxiety, weight changes — and it is also the most underdiagnosed. A single blood cortisol gives you one number at one moment; the DUTCH Adrenal gives you the entire shape of the curve, plus the body's ability to produce and clear cortisol.
If you have been told your bloods are “normal” but still feel persistently flat, hyper, or both at the wrong times of day, this is the test that turns vague stress into a specific clinical pattern you can actually work with.
Why Elemental Health and Nutrition?
Rohan has been interpreting DUTCH hormone panels for over a decade. When you choose Test + 60-min Telehealth Consult, every result is reviewed in the context of your full clinical picture — symptoms, lifestyle, prior labs, hormone status and family history. Your appointment delivers a detailed explanation of your cortisol pattern, what it means for your symptoms, and a targeted plan including herbal medicine, nutritional supplementation and lifestyle strategies.
