DUTCH Adrenal Profile
$381.00
Comprehensive dried urine test measuring cortisol and cortisone patterns throughout the day, plus cortisol metabolites. Ideal for assessing adrenal function, stress response, and HPA axis dysregulation.
Description
What Is the DUTCH Adrenal Profile?
The DUTCH Adrenal Profile (Dried Urine Test for Comprehensive Hormones) by Precision Analytical is a specialised functional test that provides a detailed picture of your adrenal function and stress hormone patterns. Unlike a single-point blood cortisol test, the DUTCH Adrenal maps your cortisol and cortisone levels across the entire day — revealing how your body produces, metabolises, and clears stress hormones over a full diurnal cycle.
This test is considered the clinical gold standard for assessing HPA (hypothalamic-pituitary-adrenal) axis function and is one of the most commonly ordered tests at Elemental Health & Nutrition for patients presenting with fatigue, sleep disturbance, anxiety, and stress-related symptoms.
What Does It Measure?
Diurnal Free Cortisol Pattern (4 points)
Waking, morning, afternoon, and evening free cortisol levels — mapped against reference ranges to identify abnormal cortisol curves including flat-line patterns, inverted rhythms, or elevated evening cortisol.
Diurnal Free Cortisone Pattern (4 points)
Cortisone is the inactive form of cortisol. Measuring both hormones reveals how efficiently your body converts between active and inactive forms — a process governed by the 11β-HSD enzyme system.
Cortisol Metabolites
Total cortisol production measured via metabolites (a-THF, b-THF, b-THE, a-THE). This is critical because free cortisol alone can appear normal even when total cortisol production is significantly elevated or depressed.
DHEA-S
The primary adrenal androgen and a key marker of adrenal reserve. Low DHEA-S relative to cortisol can indicate chronic stress and adrenal depletion.
Cortisol Awakening Response (CAR) — Optional Add-On
A specialised measurement taken at waking and 30 minutes post-waking to assess the acute cortisol spike that occurs upon rising. Clinically useful for evaluating HPA axis reactivity, depression risk, and chronic fatigue.
Who Should Consider This Test?
This test is particularly valuable for patients experiencing:
• Persistent fatigue — especially “wired but tired” patterns or morning exhaustion
• Sleep disturbance — difficulty falling asleep, waking at 2–4 AM, or unrefreshing sleep
• Anxiety, irritability, or feeling overwhelmed by minor stressors
• Afternoon energy crashes and sugar/caffeine cravings
• Chronic stress — work, relationship, or health-related
• Brain fog and poor concentration
• Recurrent illness or slow recovery from infection
• History of burnout, shift work, or prolonged high-demand periods
• Unexplained weight gain — particularly around the midsection
Sample Collection
Sample type: Dried urine on filter paper strips
Collection method: 4–5 urine samples collected at home over a 24-hour period (waking, morning, afternoon, evening, and optional bedtime)
Fasting required: No
Diet restrictions: Avoid excessive fluid intake around collection times
Medications: Some medications and supplements may need to be paused — Rohan will advise during your consultation
Turnaround Time
Results are typically returned within 4 weeks from the date the laboratory receives your sample. Samples are processed at Precision Analytical’s CLIA-certified laboratory in the United States.
What Happens After You Order
1. Kit dispatched — Your DUTCH collection kit is posted directly to your door with full instructions.
2. Collect at home — Follow the simple guide to collect your dried urine samples across the day.
3. Post back — Send your completed kit to the laboratory using the prepaid return envelope.
4. Results released to you — If you’re an existing patient, Rohan will go through the result with you at your next appointment. If you have your own practitioner, you’re welcome to order through Elemental Health and share the results with them directly.
Why Choose Elemental Health?
Rohan has been interpreting DUTCH hormone panels for over a decade. Every result is reviewed in the context of your full clinical picture — not just compared against lab reference ranges. Your results appointment includes a detailed explanation of your cortisol pattern, what it means for your symptoms, and a targeted naturopathic treatment plan including herbal medicine, nutritional supplementation, and lifestyle strategies.
